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Chemical Synthesis and NMR Characterization of Non Steroidal Mimics of an Estradiol Derivative Used as Inhibitor of 17beta-Hydroxysteroid Dehydrogenase Type 1

机译：化学合成和NMR表征的非甾体类模拟物的雌二醇衍生物用作17β-羟基类固醇脱氢酶1型的抑制剂。

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Donald Poirier; Alexandre Trottier; Guy Bertrand Djigoué; Charles Ouellet; René Maltais;
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1. Chemical Synthesis and NMR Characterization of Non Steroidal Mimics of an Estradiol Derivative Used as Inhibitor of 17beta-Hydroxysteroid Dehydrogenase Type 1 [J] . Guy Bertrand Djigoué, René Maltais, Charles Ouellet, International Journal of Chemistry . 2012,第6期

机译：化学合成和NMR表征的类固醇衍生物的类固醇衍生物用作17β-羟基类固醇脱氢酶的抑制剂。
2. Chemical synthesis, characterisation and biological evaluation of furanic-estradiol derivatives as inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. [J] . Farhane S, Laplante Y, Poirier D Medicinal chemistry . 2011,第2期

机译：呋喃-雌二醇衍生物作为17β-羟类固醇脱氢酶1型抑制剂的化学合成，表征和生物学评估
3. Androsterone derivatives substituted at position 16: chemical synthesis, inhibition of type 3 17beta-hydroxysteroid dehydrogenase, binding affinity for steroid receptors and proliferative/antiproliferative activity on Shionogi (AR+) cells. [J] . Tchedam Ngatcha B, Luu The V, Poirier D Journal of enzyme inhibition and medicinal chemistry. . 2002,第3期

机译：在位置16处取代的雄甾酮衍生物化学合成，对3型17β-羟基类固醇脱氢酶的抑制，对类固醇受体的结合亲和力和对Shionogi（AR +）细胞的增殖/抗增殖活性。
4. Chemically amplified resists based on the norbornene copolymers with steroid derivatives [C] . Jin-Baek Kim, Bum-Wook Lee, Jae-Sung Kang, Conference on advances in resist technology and processing . 1999

机译：基于与类固醇衍生物的降冰片烯共聚物的化学放大抗性
5. Estrogen and androgen discrimination by human 17beta-hydroxysteroid dehydrogenase type 1 and a conserved cofactor binding mode in the short-chain dehydrogenase/reductase family. [D] . Shi, Rong. 2004

机译：在短链脱氢酶/还原酶家族中，人1型17β-羟基类固醇脱氢酶和保守的辅因子结合模式对雌激素和雄激素的区分。
6. Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3alpha/7alpha/7beta/17beta/20beta/21-HSD. [O] . Naeem Shafqat, Hanns-Ulrich Marschall, Charlotta Filling, 2003

机译：人类和果蝇10型17β-羟基类固醇脱氢酶（HSD）的扩大的底物筛选揭示了胆汁酸和类固醇激素代谢的多种特异性：多功能3alpha / 7alpha / 7beta / 17beta / 20beta / 21-HSD的表征。
7. Pharmacophore aided hit identification, structural optimization and biological evaluation of benzothiazole derivatives as new potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 [O] . Spadaro Alessandro 2011

机译：药理学帮助苯并噻唑衍生物作为17β-羟基类固醇脱氢酶1型的新型有效和选择性非类固醇抑制剂的命中鉴定，结构优化和生物学评估
8. Synthesis of Selective Inhibitors of 17beta-Hydroxysteroid Dehydrogenase [R] . Barlow, J. P. , Vander Jagt, D. L. 2002

机译：17β-羟基类固醇脱氢酶选择性抑制剂的合成

Chemical Synthesis and NMR Characterization of Non Steroidal Mimics of an Estradiol Derivative Used as Inhibitor of 17beta-Hydroxysteroid Dehydrogenase Type 1

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